What is the most recommended procedures for the use of heparine and protamine?
Please specify when and how each is given during the treatment. I really apreciate the
responses.

Brian,

Here is a list of anticoagulation for hemodialysis references:

1. Daugirdas, J.T. and Ing, T.S. Handbook of Dialysis, 2d ed., Little, Brown, and Company, New York, 1994, pp. 121-136 You can order this book from amazon.com

2. Lancaster, L.E., (Eds.) American Nephrology Nurses� Association Core Curriculum for Nephrology Nursing, 3d ed., American Nephrology Nurses� Association, New Jersey, 1995, pp. 217-218. ANNA web site

3. Gutch C.F., Stoner, M.H., and Corea, A.L. (Eds.) Review of Hemodialysis for Nurses and Dialysis Personal, 6th ed., Mosby, Missouri , 1999, pp. 134-141. Link to order this book is on the RenalWEB Topic Dialysis Technician Resources page under Essentials and Classics. You can order this book from amazon.com

4. Ouseph, R., Brier M.E., Ward, R.A., Improved dialyzer reuse after use of a population pharmacodynamic model to determine heparin doses. Am J Kidney Dis 2000 Jan;35 (1) pp.89-94 PubMed abstract

5. Ward, R.A., Heparinization for routine hemodialysis. Adv Ren Replace Ther 1995 Oct; 2(4); 362-70 PubMed abstract

Note: Protamine must be administrated slowly to prevent the very serious adverse reactions of hypotension, bradycardia, and circulatory collapse. Check for any known allergies to fish prior to administration of protamine due to the possibility of cross sensitivity reactions.

Deborah


[This message has been edited by Deborah Brouwer (edited 07-11-2000).]